Which of the following is NOT a sign of infection?

Clear discharge is not typically considered a sign of infection. Infections often produce purulent or cloudy discharge, which can be indicative of the presence of bacteria and inflammation. Clear discharge may occur in various contexts that do not indicate an infection, such as in the case of allergies, mild irritation, or normal bodily processes, like the secretion of mucus.

On the other hand, symptoms like fatigue, nausea, and pain or tenderness can be signs of infection, as they generally arise from the body's response to pathogens. Fatigue is a common response as the body uses energy to fight off the infection, while nausea may result from the release of toxins or the body’s overall stress response. Pain or tenderness often indicates inflammation or an area of infection in the body.