What is the main cause of cholecystitis?

The primary cause of cholecystitis is gallstones. When gallstones form in the gallbladder, they can block the cystic duct, which is the passage that allows bile to leave the gallbladder. This blockage can lead to inflammation of the gallbladder, resulting in cholecystitis. The presence of gallstones is the most prevalent factor contributing to this condition, as they disrupt normal bile flow and lead to increased pressure and inflammation in the gallbladder.

Although infections, whether viral or bacterial, can occur alongside instances of cholecystitis, they are often secondary consequences rather than primary causes. An autoimmune response is also not a typical cause of cholecystitis; the main factor remains the blockage and irritation caused by gallstones. Understanding the central role of gallstones helps in effectively diagnosing and treating cholecystitis, along with the management of any complications arising from the inflammation.